Larry Wayne Willoughby, 62, of Isola, passed away Friday, November 5, 2021, at his home.  Larry was born March 5, 1959, in Leland, to Arthur Garland "Boots" Willoughby and Erma Dean Duke Willoughby. He worked as a truck driver for Gresham McPherson Oil in Belzoni for several years and worked at ConAgra in Isola for many years. Larry was a very likeable person. He was born with the gift of gab and could make anyone like him.  He was preceded in death by his father, A.G. "Boots" Willoughby. He is survived by his mother, Erma Dean Nichols of Indianola; three children, Timothy (Magen) Willoughby of Louise, Ashley (Marcus) McPhail of Madison, and Austin Willoughby of Ohio; brother, Don Willoughby of Arizona; sister, Debbie Willoughby of Indianola; four grandchildren, Bratton Willoughby, Peyton Willoughby, Levi McPhail, and Benjamin McPhail; and a host of friends. A memorial service will be held at 10:00 am, Wednesday, November 10, 2021, at First Baptist Church in Isola. Burton Funeral Home of Indianola has been entrusted with arrangements.